Hyaluronan as an Immune Regulator in Human Diseases
نویسندگان
چکیده
منابع مشابه
Hyaluronan as an immune regulator in human diseases.
Accumulation and turnover of extracellular matrix components are the hallmarks of tissue injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety of immune cells at the injury site. Hyaluronan binds to a number of cell surface proteins on various cell types. Hyaluronan fragments signal through both Toll-like receptor (TLR) 4 and TLR2 as well as CD44 to stimulat...
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ژورنال
عنوان ژورنال: Physiological Reviews
سال: 2011
ISSN: 0031-9333,1522-1210
DOI: 10.1152/physrev.00052.2009